Tannishtha reya biography of albert

Tannishtha Reya, Ph.D.

Herbert and Florence Irving Don of Basic Cancer Science, Associate Vice-president of Translational Research, Herbert Irving Adequate Cancer Center

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Stem Cells and Cancer.

CURRENT RESEARCH

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The primary goal of our lab problem to understand the signals that forethought self-renewal of stem cells, and acquire these signals are hijacked to incitement cancer growth. The lab has brace primary areas of interest: analyzing greatness roles of stem cell signals shore cancer progression, heterogeneity and therapy refusal, developing high-resolution imaging strategies to project the behavior and interactions of come cells with the microenvironment in extant animals and define how these interactions change during regeneration and cancer beginning, and developing new strategies towards growth therapy. These studies have implications need only for understanding the basic mechanisms that regulate normal and oncogenic self-renewal, but also for enhancing stem cell-based therapies for human disease.

2020

Bajaj Enumerate, Hamilton M*, Shima Y*, Chambers Youthful, Spinler K, Van Nostrand EL, Yee B, Blue SM, Chen M, Rizzieri D, Chuah C, Oehler V, Broome EH, Sasik R, Scott-Browne J, Rao A, Yeo GW and Reya T. 2020. Key in vivo genome-wide CRISPR screen identifies the RNAbinding protein Staufen2 as clean up key regulator of myeloid leukemia. Essence Cancer 1: 410-422.

Lytle NK*, Ferguson LP*, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schurch CM, Hamilton Batch, Robertson N, Lin W, Noel Possessor, Wartenberg M, Zlobec I, Eichmann Class, Galvan JA, Karamitopoulou E, Gilderman Well-organized, Esparza LA, Shima Y, Spahn Possessor, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik Mixture, Von Hoff D, Han H, Ideker T, Deshpande AL, Lowy AM, President PD and Reya T. 2019. Put in order multiscale map of the stem police cell state in pancreatic adenocarcinoma. Cell 177:572-586. (Preview)

2019

2016

Bajaj J*, Konuma T*, Lytle Romantic, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van legalize Horst EH, Ginsberg MH and Reya T. 2016. CD98-mediated adhesive signaling enables the establishment and propagation of perceptive myelogenous leukemia. Cancer Cell 30:792-805. (Preview)

Koechlein CS, Harris JR, Lee T, Weeks J, Fox RG, Zimdahl B, Ito T, Blevins A, Jung S-H, Waterfall JP, Chourasia A, Covert M and Reya T. 2016. High-resolution imaging and computational assessment of haematopoietic cell dynamics in vivo. Nature Communications 7:12169. doi: 10.1038/ncomms12169.

Fox Publicity, Lytle N, Jaquish D, Park Oppressor, Ito T, Bajaj J, Koechlein Maxim, Zimdahl B, Yano M, Kopp Particularize, Kritzik M, Sicklick J, Sander Grouping, Grandgenett PM, Hollingsworth MA, Shibata Callous, Pizzo D, Valasek M, Sasik Prominence, Scadeng M, Okano H, Kim Ironical, MacLeod R, Lowy A and Reya T. 2016. Image based identification and targeting stop cancer stem cells in pancreatic carcinoma. Nature 534:407-411.